At the request of Father Jérémie de Paglietta, three sisters landed in Seychelles in January 1861, on board the ‘Lucie’: Mother Denise Desesquelles, Sister Saint Victor Escad and Sister Saint Denis Berthoud.
They opened the first public school for girls and they set up an orphanage.
The landslide of 11-12 October 1862 swept away two of the nuns.

In 1923 during excavation works for the extension of the Cathedral, workers found their bones.

In 1863, four nuns arrived from La Réunion: Mother Honorine Denis, Sisters Antonin Benoît, Chantal Robbe and Paul Hoareau.
In 1865, Father Ignace, Apostolic Prefect, bought the site at St Joseph Street for the sisters. Under the impetus of Mother Saint Aubin, they opened a free school for girls, (closed in 1947), a boarding school, a sewing room, a bakery and a printing house. Seychelles Hospital was opened in 1874. Two sisters worked there. The community at the hospital was closed in 1977, but the nuns still work there.

1875: Setting up of a community at Anse Royale. Up to 1911, 25 Seychellois nuns were trained in the noviciate set up in 1887. Under the direction of the new superior, Mother Sainte Marie des Anges, the schools flourished. Bishop Marc Hudrisier gave the sisters, then 60 in number, the responsibility of the Mission schools, except for those at Baie Sainte Anne, Praslin and Port-Glaud.

1996: Setting up of the Roche Caïman community. With the expansion of the Vice-Province in 1998, the community went on mission: with two other nuns, Sister Anne Faure settled in Mwanzugi (Tanzania) and in Tabora in

2003. Two other Seychelloises joined her: Sisters Agnès and Aline. On 20th February 2009, the Provincial House community was formed.